ul_946----
Record details: Hide
PPBD protein
Gene name YWHAZ
Synonyms KCIP-1; Protein kinase C inhibitor protein 1
GO annotations GO_component:
GO_function:protein domain specific binding; transcription factor binding [PMID 16114898]
GO_process:
RefSeq accession NP_003397
SwissProt accession P63104
Substrate protein
Gene name ADAM22
Synonyms A disintegrin and metalloproteinase domain 22; Metalloproteinase-disintegrin ADAM22-3; Metalloproteinase-like, disintegrin-like, and cysteine-rich protein 2
GO annotations GO_component: integral to membrane [PMID 9693107]; membrane
GO_function:integrin binding [PMID 9693107]; metalloendopeptidase activity; protein binding
GO_process: cell adhesion; central nervous system development [PMID 9693107]; negative regulation of cell adhesion [PMID 9693107]; proteolysis
RefSeq accession NP_068369
SwissProt accession Q9P0K1
GO Pathway:
GO:0007155     cell adhesion
Sequence:(RefSeq accession:NP_068369; substrate region highlighted if known)
1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
MQAAVAVSVP FLLLCVLGTC PPARCGQAGD ASLMELEKRK ENRFVERQSI VPLRLIYRSG
GEDESRHDAL DTRVRGDLGG PQLTHVDQAS FQVDAFGTSF ILDVVLNHDL LSSEYIERHI
EHGGKTVEVK GGEHCYYQGH IRGNPDSFVA LSTCHGLHGM FYDGNHTYLI EPEENDTTQE
DFHFHSVYKS RLFEFSLDDL PSEFQQVNIT PSKFILKPRP KRSKRQLRRY PRNVEEETKY
IELMIVNDHL MFKKHRLSVV HTNTYAKSVV NMADLIYKDQ LKTRIVLVAM ETWATDNKFA
ISENPLITLR EFMKYRRDFI KEKSDAVHLF SGSQFESSRS GAAYIGGICS LLKGGGVNEF
GKTDLMAVTL AQSLAHNIGI ISDKRKLASG ECKCEDTWSG CIMGDTGYYL PKKFTQCNIE
EYHDFLNSGG GACLFNKPSK LLDPPECGNG FIETGEECDC GTPAECVLEG AECCKKCTLT
QDSQCSDGLC CKKCKFQPMG TVCREAVNDC DIRETCSGNS SQCAPNIHKM DGYSCDGVQG
ICFGGRCKTR DRQCKYIWGQ KVTASDKYCY EKLNIEGTEK GNCGKDKDTW IQCNKRDVLC
GYLLCTNIGN IPRLGELDGE ITSTLVVQQG RTLNCSGGHV KLEEDVDLGY VEDGTPCGPQ
MMCLEHRCLP VASFNFSTCL SSKEGTICSG NGVCSNELKC VCNRHWIGSD CNTYFPHNDD
AKTGITLSGN GVAGTNIIIG IIAGTILVLA LILGITAWGY KNYREQRQLP QGDYVKKPGD
GDSFYSDIPP GVSTNSASSS KKRSNGLSHS WSERIPDTKH ISDICENGRP RSNSWQGNLG
GNKKKIRGKR FRPRSNSTET LSPAKSPSSS TGSIASSRKY PYPMPPLPDE DKKVNRQSAR
LWETSI
Records:
Category Evidence Reference
A Mutagenesis Zhu P, Sun Y, Xu R, Sang Y, Zhao J, Liu G, Cai L, Li C, Zhao S., The interaction between ADAM 22 and 14-3-3zeta: regulation of cell adhesion and spreading., [12589811]
End of Record Details