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PPBD protein
Gene name YWHAB( Description: tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide. )
Synonyms GW128; HS1; KCIP-1; Protein 1054; Protein kinase C inhibitor protein 1
GO annotations GO_component: cytoplasm [PMID 12963375]; perinuclear region [PMID 12963375]
GO_function:monooxygenase activity; protein domain specific binding
GO_process:
RefSeq accession NP_003395
SwissProt accession P31946
Substrate protein
Gene name PTPN3( Description: protein tyrosine phosphatase, non-receptor type 3. )
Synonyms DKFZp686N0569; EC 3.1.3.48; PTP-H1; PTPH1; Protein-tyrosine phosphatase H1
GO annotations GO_component: cytoplasm; cytoskeleton; membrane
GO_function:cytoskeletal protein binding; hydrolase activity; protein binding; protein tyrosine phosphatase activity [PMID 1648725]; structural molecule activity
GO_process: protein amino acid dephosphorylation [PMID 1648725]
RefSeq accession NP_002820
SwissProt accession P26045
GO Pathway:
GO:0004725     protein tyrosine phosphatase activity
Sequence:(RefSeq accession:NP_002820; substrate region highlighted if known)
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MTSRLRALGG RINNIRTSEL PKEKTRSEVI CSIHFLDGVV QTFKVTKQDT GQVLLDMVHN
HLGVTEKEYF GLQHDDDSVD SPRWLEASKA IRKQLKGGFP CTLHFRVRFF IPDPNTLQQE
QTRHLYFLQL KMDICEGRLT CPLNSAVVLA SYAVQSHFGD YNSSIHHPGY LSDSHFIPDQ
NEDFLTKVES LHEQHSGLKQ SEAESCYINI ARTLDFYGVE LHSGRDLHNL DLMIGIASAG
VAVYRKYICT SFYPWVNILK ISFKRKKFFI HQRQKQAESR EHIVAFNMLN YRSCKNLWKS
CVEHHTFFQA KKLLPQEKNV LSQYWTMGSR NTKKSVNNQY CKKVIGGMVW NPAMRRSLSV
EHLETKS
LPS RSPPITPNWR SPRLRHEIRK PRHSSADNLA NEMTYITETE DVFYTYKGSL
APQDSDSEVS QNRSPHQESL SENNPAQSYL TQKSSSSVSP SSNAPGSCSP DGVDQQLLDD
FHRVTKGGST EDASQYYCDK NDNGDSYLVL IRITPDEDGK FGFNLKGGVD QKMPLVVSRI
NPESPADTCI PKLNEGDQIV LINGRDISEH THDQVVMFIK ASRESHSREL ALVIRRRAVR
SFADFKSEDE LNQLFPEAIF PMCPEGGDTL EGSMAQLKKG LESGTVLIQF EQLYRKKPGL
AITFAKLPQN LDKNRYKDVL PYDTTRVLLQ GNEDYINASY VNMEIPAANL VNKYIATQGP
LPHTCAQFWQ VVWDQKLSLI VMLTTLTERG RTKCHQYWPD PPDVMNHGGF HIQCQSEDCT
IAYVSREMLV TNTQTGEEHT VTHLQYVAWP DHGVPDDSSD FLEFVNYVRS LRVDSEPLLV
HCSAGIGRTG VLVTMETAMC LTERNLPIYP LDIVRKMRDQ RAMMVQTSSQ YKFVCEAILR
VYEEGLVQML DPS
Records:
Category Evidence Reference
A Mutagenesis Zhang SH, Kobayashi R, Graves PR, Piwnica-Worms H, Tonks NK., Serine phosphorylation-dependent association of the band 4.1-related protein-tyrosine phosphatase PTPH1 with 14-3-3beta protein., [9341175]
End of Record Details