ABHD12 / TRP channels
Name: Monoacylglycerol lipase ABHD12
(ABHD12)
Official Symbol: ABHD12
provided by HGNC
Function:
Has 2-arachidonoylglycerol hydrolase activity (By similarity). May be a regulator of endocannabinoid signaling pathways (By similarity).
Source: Reorganizing the protein space at the Universal Protein Resource (UniProt)
Nucleic Acids Res. 40: D71-D75 (2012).
Species | External DB | |||||||||
---|---|---|---|---|---|---|---|---|---|---|
Entrez Gene | UniprotKB | DIP | IntAct | MINT | BioGRID | STRING | IUPHAR-DB | KEGG | OMIM | |
Human
|
26090 | Q8N2K0 | Q8N2K0 | UNK-5452996 | 117541 | Q8N2K0 | hsa:26090 | |||
Mouse
|
76192 | Q99LR1 | MINT-4124321 | 218015 | Q99LR1 | mmu:76192 | ||||
Rat
|
499913 | Q6AYT7 | 271221 | Q6AYT7 | rno:499913 |
PPI pairs:
Biological Process:
No information in Gene Ontology
Source: The Gene Ontology Consortium. Gene ontology: tool for the unification of biology. Nat. Genet.. May 2000;25(1):25-9.
World Wide Web URL: http://www.geneontology.org/
World Wide Web URL: http://www.geneontology.org/
Disease:
- OMIM:613599 : Polyneuropathy, hearing loss, ataxia, retinitis pigmentosa, and cataract (OMIM:612674 )
Source: Online Mendelian Inheritance in Man, OMIM®. McKusick-Nathans Institute of Genetic Medicine,
Johns Hopkins University (Baltimore, MD), May, 2012.
World Wide Web URL: http://omim.org/
World Wide Web URL: http://omim.org/
Screening Validation: In vitro validation Validation: In vivo validation Characterization Functional consequence | top |
Screening | ||||||||||
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Experimental screening | Non-experimental screening | Reference | ||||||||
TRP channel construct | Interactor source | |||||||||
TRP channel | Interactor | Method | Species | Region | Species | Organ/tissue | Sample type | |||
TRPP1 | ABHD12 | Affinity purification-mass spectrometry | Mouse | Not specified | Mouse | Vascular smooth muscle | MOVAS lysates | 19879844 |
(:
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