CHERP / TRP channels
Name: Calcium homeostasis endoplasmic reticulum protein
(CHERP)
Official Symbol: CHERP
provided by HGNC
Function:
Involved in calcium homeostasis, growth and proliferation.
Source: Reorganizing the protein space at the Universal Protein Resource (UniProt)
Nucleic Acids Res. 40: D71-D75 (2012).
Species | External DB | |||||||||
---|---|---|---|---|---|---|---|---|---|---|
Entrez Gene | UniprotKB | DIP | IntAct | MINT | BioGRID | STRING | IUPHAR-DB | KEGG | OMIM | |
Human
|
10523 | Q8IWX8 | DIP-44945N | Q8IWX8 | MINT-4115833 | 115778 | Q8IWX8 | hsa:10523 | ||
Mouse
|
27967 | Q8CGZ0 | DIP-54829N | Q8CGZ0 | MINT-4115833 | 205695 | Q8CGZ0 | mmu:27967 | ||
Rat | 290614 | 253246 | rno:290614 |
PPI pairs:
Biological Process:
- GO:0008285 : negative regulation of cell proliferation
- GO:0007399 : nervous system development
- GO:0051533 : positive regulation of NFAT protein import into nucleus
- GO:0051209 : release of sequestered calcium ion into cytosol
- GO:0006396 : RNA processing
Source: The Gene Ontology Consortium. Gene ontology: tool for the unification of biology. Nat. Genet.. May 2000;25(1):25-9.
World Wide Web URL: http://www.geneontology.org/
World Wide Web URL: http://www.geneontology.org/
Disease:
No information in OMIM
Source: Online Mendelian Inheritance in Man, OMIM®. McKusick-Nathans Institute of Genetic Medicine,
Johns Hopkins University (Baltimore, MD), May, 2012.
World Wide Web URL: http://omim.org/
World Wide Web URL: http://omim.org/
Screening Validation: In vitro validation Validation: In vivo validation Characterization Functional consequence | top |
Screening | ||||||||||
---|---|---|---|---|---|---|---|---|---|---|
Experimental screening | Non-experimental screening | Reference | ||||||||
TRP channel construct | Interactor source | |||||||||
TRP channel | Interactor | Method | Species | Region | Species | Organ/tissue | Sample type | |||
TRPV1 | CHERP | Yeast two-hybrid | Rat | 1-432 | Human | Fetal brain | cDNA library | 17074976 |
(:
click the arrow icon to show interactions only between the corresponding TRP channel and the interactor)