GLUD1 / TRP channels
Name: Glutamate dehydrogenase 1, mitochondrial
(GLUD1)
Official Symbol: GLUD1
provided by HGNC
Function:
May be involved in learning and memory reactions by increasing the turnover of the excitatory neurotransmitter glutamate (By similarity).
Source: Reorganizing the protein space at the Universal Protein Resource (UniProt)
Nucleic Acids Res. 40: D71-D75 (2012).
Species |
External DB
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Entrez Gene | UniprotKB | DIP | IntAct | MINT | BioGRID | STRING | IUPHAR-DB | KEGG | OMIM | |
Human
![]() |
2746![]() |
P00367![]() |
P00367![]() |
MINT-5005913![]() |
109008![]() |
P00367![]() |
hsa:2746![]() |
138130![]() |
||
Mouse
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14661![]() |
P26443![]() |
P26443![]() |
199956![]() |
P26443![]() |
mmu:14661![]() |
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Rat
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24399![]() |
P10860![]() |
P10860![]() |
MINT-2793533![]() |
246566![]() |
P10860![]() |
rno:24399![]() |
PPI pairs:
Biological Process:
- GO:0034641
: cellular nitrogen compound metabolic process
- GO:0006537
: glutamate biosynthetic process
- GO:0006538
: glutamate catabolic process
- GO:0032024
: positive regulation of insulin secretion
Source: The Gene Ontology Consortium. Gene ontology: tool for the unification of biology. Nat. Genet.. May 2000;25(1):25-9.
World Wide Web URL: http://www.geneontology.org/
World Wide Web URL: http://www.geneontology.org/
Disease:
- OMIM:138130
: Hyperinsulinism-hyperammonemia syndrome (OMIM:606762
)
Source: Online Mendelian Inheritance in Man, OMIM®. McKusick-Nathans Institute of Genetic Medicine,
Johns Hopkins University (Baltimore, MD), May, 2012.
World Wide Web URL: http://omim.org/
World Wide Web URL: http://omim.org/
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Screening
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Experimental screening | Non-experimental screening | Reference | ||||||||
TRP channel construct | Interactor source | |||||||||
TRP channel | Interactor | Method | Species | Region | Species | Organ/tissue | Sample type | |||
TRPC3 |
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GLUD1 | Affinity purification-mass spectrometry | Not used as a bait | Rat | Brain | Crude membranes | 18205297 |
(
:
click the arrow icon to show interactions only between the corresponding TRP channel and the interactor)
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