Idh3B / TRP channels
Name: Isocitrate dehydrogenase [NAD] subunit beta, mitochondrial
(Idh3B)
Official Symbol: IDH3B
provided by HGNC
Function:
Source: Reorganizing the protein space at the Universal Protein Resource (UniProt)
Nucleic Acids Res. 40: D71-D75 (2012).
Species | External DB | |||||||||
---|---|---|---|---|---|---|---|---|---|---|
Entrez Gene | UniprotKB | DIP | IntAct | MINT | BioGRID | STRING | IUPHAR-DB | KEGG | OMIM | |
Human
|
3420 | O43837 | O43837 | MINT-1431659 | 109646 | O43837 | hsa:3420 | 604526 | ||
Mouse
|
170718 | Q91VA7 | Q91VA7 | 228390 | Q91VA7 | mmu:170718 | ||||
Rat
|
94173 | Q68FX0 | 250169 | Q68FX0 | rno:94173 |
PPI pairs:
Biological Process:
- GO:0006103 : 2-oxoglutarate metabolic process
- GO:0006102 : isocitrate metabolic process
- GO:0006734 : NADH metabolic process
- GO:0006099 : tricarboxylic acid cycle
Source: The Gene Ontology Consortium. Gene ontology: tool for the unification of biology. Nat. Genet.. May 2000;25(1):25-9.
World Wide Web URL: http://www.geneontology.org/
World Wide Web URL: http://www.geneontology.org/
Disease:
- OMIM:604526 : Retinitis pigmentosa 46 (OMIM:612572 )
Source: Online Mendelian Inheritance in Man, OMIM®. McKusick-Nathans Institute of Genetic Medicine,
Johns Hopkins University (Baltimore, MD), May, 2012.
World Wide Web URL: http://omim.org/
World Wide Web URL: http://omim.org/
Screening Validation: In vitro validation Validation: In vivo validation Characterization Functional consequence | top |
Screening | ||||||||||
---|---|---|---|---|---|---|---|---|---|---|
Experimental screening | Non-experimental screening | Reference | ||||||||
TRP channel construct | Interactor source | |||||||||
TRP channel | Interactor | Method | Species | Region | Species | Organ/tissue | Sample type | |||
TRPC3 | Idh3B | Affinity purification-mass spectrometry | Not used as a bait | Rat | Brain | Crude membranes | 18205297 |
(:
click the arrow icon to show interactions only between the corresponding TRP channel and the interactor)