LETMD1 / TRP channels
Name: LETM1 domain-containing protein 1
(LETMD1)
Official Symbol: LETMD1
provided by HGNC
Function:
Involved in tumorigenesis and may function as a negative regulator of the p53/TP53.
Source: Reorganizing the protein space at the Universal Protein Resource (UniProt)
Nucleic Acids Res. 40: D71-D75 (2012).
| Species |
External DB
|
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|---|---|---|---|---|---|---|---|---|---|---|
| Entrez Gene | UniprotKB | DIP | IntAct | MINT | BioGRID | STRING | IUPHAR-DB | KEGG | OMIM | |
Human
|
25875 |
Q6P1Q0 |
Q6P1Q0 |
117390 |
Q6P1Q0 |
hsa:25875 |
||||
|
Mouse
|
68614 |
Q924L1 |
212953 |
Q924L1 |
mmu:68614 |
|||||
|
Rat
|
681352 |
B0K026 |
596281 |
B0K026 |
rno:681352 |
|||||
PPI pairs:
Biological Process:
No information in Gene Ontology
Source: The Gene Ontology Consortium. Gene ontology: tool for the unification of biology. Nat. Genet.. May 2000;25(1):25-9.
World Wide Web URL: http://www.geneontology.org/
World Wide Web URL: http://www.geneontology.org/
Disease:
No information in OMIM
Source: Online Mendelian Inheritance in Man, OMIM®. McKusick-Nathans Institute of Genetic Medicine,
Johns Hopkins University (Baltimore, MD), May, 2012.
World Wide Web URL: http://omim.org/
World Wide Web URL: http://omim.org/
 Screening
Validation: In vitro validation
Validation: In vivo validation
Characterization
Functional consequence
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top
|
Screening
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|---|---|---|---|---|---|---|---|---|---|---|
| Experimental screening | Non-experimental screening | Reference | ||||||||
| TRP channel construct | Interactor source | |||||||||
| TRP channel | Interactor | Method | Species | Region | Species | Organ/tissue | Sample type | |||
| TRPP1 |
|
LETMD1 | Affinity purification-mass spectrometry | Mouse | Not specified | Mouse | Vascular smooth muscle | MOVAS lysates | 19879844 | |
(:
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:
click the arrow icon to show interactions only between the corresponding TRP channel and the interactor)