MDH2 / TRP channels
Name: Malate dehydrogenase, mitochondrial
(MDH2)
Official Symbol: MDH2
provided by HGNC
Function:
Source: Reorganizing the protein space at the Universal Protein Resource (UniProt)
Nucleic Acids Res. 40: D71-D75 (2012).
Species | External DB | |||||||||
---|---|---|---|---|---|---|---|---|---|---|
Entrez Gene | UniprotKB | DIP | IntAct | MINT | BioGRID | STRING | IUPHAR-DB | KEGG | OMIM | |
Human
|
4191 | P40926 | P40926 | MINT-1408946 | 110356 | P40926 | hsa:4191 | 154100 | ||
Mouse
|
17448 | P08249 | P08249 | 201467 | P08249 | mmu:17448 | ||||
Rat
|
81829 | P04636 | P04636 | 249687 | P04636 | rno:81829 |
PPI pairs:
Biological Process:
- GO:0044262 : cellular carbohydrate metabolic process
- GO:0006094 : gluconeogenesis
- GO:0006475 : internal protein amino acid acetylation
- GO:0006108 : malate metabolic process
- GO:0006734 : NADH metabolic process
- GO:0006107 : oxaloacetate metabolic process
- GO:0006099 : tricarboxylic acid cycle
Source: The Gene Ontology Consortium. Gene ontology: tool for the unification of biology. Nat. Genet.. May 2000;25(1):25-9.
World Wide Web URL: http://www.geneontology.org/
World Wide Web URL: http://www.geneontology.org/
Disease:
No information in OMIM
Source: Online Mendelian Inheritance in Man, OMIM®. McKusick-Nathans Institute of Genetic Medicine,
Johns Hopkins University (Baltimore, MD), May, 2012.
World Wide Web URL: http://omim.org/
World Wide Web URL: http://omim.org/
Screening Validation: In vitro validation Validation: In vivo validation Characterization Functional consequence | top |
Screening | ||||||||||
---|---|---|---|---|---|---|---|---|---|---|
Experimental screening | Non-experimental screening | Reference | ||||||||
TRP channel construct | Interactor source | |||||||||
TRP channel | Interactor | Method | Species | Region | Species | Organ/tissue | Sample type | |||
TRPC3 | MDH2 | Affinity purification-mass spectrometry | Not used as a bait | Rat | Brain | Crude membranes | 18205297 |
(:
click the arrow icon to show interactions only between the corresponding TRP channel and the interactor)