MDH2 / TRP channels
Name: Malate dehydrogenase, mitochondrial
(MDH2)
Official Symbol: MDH2
provided by HGNC
Function:
Source: Reorganizing the protein space at the Universal Protein Resource (UniProt)
Nucleic Acids Res. 40: D71-D75 (2012).
| Species |
External DB
|
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Entrez Gene | UniprotKB | DIP | IntAct | MINT | BioGRID | STRING | IUPHAR-DB | KEGG | OMIM | |
Human
|
4191 |
P40926 |
P40926 |
MINT-1408946 |
110356 |
P40926 |
hsa:4191 |
154100 |
||
Mouse
|
17448 |
P08249 |
P08249 |
201467 |
P08249 |
mmu:17448 |
||||
Rat
|
81829 |
P04636 |
P04636 |
249687 |
P04636 |
rno:81829 |
||||
PPI pairs:
Biological Process:
- GO:0044262
: cellular carbohydrate metabolic process - GO:0006094
: gluconeogenesis - GO:0006475
: internal protein amino acid acetylation - GO:0006108
: malate metabolic process - GO:0006734
: NADH metabolic process - GO:0006107
: oxaloacetate metabolic process - GO:0006099
: tricarboxylic acid cycle
Source: The Gene Ontology Consortium. Gene ontology: tool for the unification of biology. Nat. Genet.. May 2000;25(1):25-9.
World Wide Web URL: http://www.geneontology.org/
World Wide Web URL: http://www.geneontology.org/
Disease:
No information in OMIM
Source: Online Mendelian Inheritance in Man, OMIM®. McKusick-Nathans Institute of Genetic Medicine,
Johns Hopkins University (Baltimore, MD), May, 2012.
World Wide Web URL: http://omim.org/
World Wide Web URL: http://omim.org/
Screening
Validation: In vitro validation
Validation: In vivo validation
Characterization
Functional consequence
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top
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Screening
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|---|---|---|---|---|---|---|---|---|---|---|
| Experimental screening | Non-experimental screening | Reference | ||||||||
| TRP channel construct | Interactor source | |||||||||
| TRP channel | Interactor | Method | Species | Region | Species | Organ/tissue | Sample type | |||
| TRPC3 |
|
MDH2 | Affinity purification-mass spectrometry | Not used as a bait | Rat | Brain | Crude membranes | 18205297 | ||
(
:
click the arrow icon to show interactions only between the corresponding TRP channel and the interactor)
:
click the arrow icon to show interactions only between the corresponding TRP channel and the interactor)







Screening