NCAM1 / TRP channels
Name: Neural cell adhesion molecule 1
(NCAM1)
Official Symbol: NCAM1
provided by HGNC
Function:
This protein is a cell adhesion molecule involved in neuron-neuron adhesion, neurite fasciculation, outgrowth of neurites, etc.
Source: Reorganizing the protein space at the Universal Protein Resource (UniProt)
Nucleic Acids Res. 40: D71-D75 (2012).
Species | External DB | |||||||||
---|---|---|---|---|---|---|---|---|---|---|
Entrez Gene | UniprotKB | DIP | IntAct | MINT | BioGRID | STRING | IUPHAR-DB | KEGG | OMIM | |
Human
|
4684 | P13591 | DIP-59530N | P13591 | 110764 | P13591 | hsa:4684 | 116930 | ||
Mouse
|
17967 | P13595 | P13595 | MINT-1176881 | 201699 | P13595 | mmu:17967 | |||
Rat
|
24586 | P13596 | P13596 | MINT-2635713 | 246729 | P13596 | rno:24586 |
PPI pairs:
Biological Process:
- GO:0007411 : axon guidance
- GO:0007155 : cell adhesion
- GO:0034109 : homotypic cell-cell adhesion
- GO:0060333 : interferon-gamma-mediated signaling pathway
- GO:0050850 : positive regulation of calcium-mediated signaling
- GO:0001928 : regulation of exocyst assembly
Source: The Gene Ontology Consortium. Gene ontology: tool for the unification of biology. Nat. Genet.. May 2000;25(1):25-9.
World Wide Web URL: http://www.geneontology.org/
World Wide Web URL: http://www.geneontology.org/
Disease:
No information in OMIM
Source: Online Mendelian Inheritance in Man, OMIM®. McKusick-Nathans Institute of Genetic Medicine,
Johns Hopkins University (Baltimore, MD), May, 2012.
World Wide Web URL: http://omim.org/
World Wide Web URL: http://omim.org/
Screening Validation: In vitro validation Validation: In vivo validation Characterization Functional consequence | top |
Screening | ||||||||||
---|---|---|---|---|---|---|---|---|---|---|
Experimental screening | Non-experimental screening | Reference | ||||||||
TRP channel construct | Interactor source | |||||||||
TRP channel | Interactor | Method | Species | Region | Species | Organ/tissue | Sample type | |||
TRPC3 | NCAM1 | Affinity purification-mass spectrometry | Not used as a bait | Rat | Brain | Crude membranes | 18205297 |
(:
click the arrow icon to show interactions only between the corresponding TRP channel and the interactor)