Neurabin-1 / TRP channels
Name: Neurabin-1
(Neurabin-1)
Official Symbol: PPP1R9A
provided by HGNC
Function:
Binds to actin filaments (F-actin) and shows cross-linking activity. Binds along the sides of the F-actin. May be involved in neurite formation. Inhibits protein phosphatase 1-alpha activity (By similarity).
Source: Reorganizing the protein space at the Universal Protein Resource (UniProt)
Nucleic Acids Res. 40: D71-D75 (2012).
| Species |
External DB
|
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|---|---|---|---|---|---|---|---|---|---|---|
| Entrez Gene | UniprotKB | DIP | IntAct | MINT | BioGRID | STRING | IUPHAR-DB | KEGG | OMIM | |
Human
|
55607 |
Q9ULJ8 |
DIP-41131N |
Q9ULJ8 |
MINT-106754 |
120747 |
Q9ULJ8 |
hsa:55607 |
602468 |
|
Mouse
|
243725 |
Q7TN74 |
DIP-44293N |
MINT-4600266 |
232551 |
Q7TN74 |
mmu:243725 |
|||
Rat
|
84685 |
O35867 |
DIP-40850N |
MINT-107263 |
250039 |
O35867 |
rno:84685 |
|||
PPI pairs:
Biological Process:
- GO:0030154
: cell differentiation - GO:0007399
: nervous system development
Source: The Gene Ontology Consortium. Gene ontology: tool for the unification of biology. Nat. Genet.. May 2000;25(1):25-9.
World Wide Web URL: http://www.geneontology.org/
World Wide Web URL: http://www.geneontology.org/
Disease:
No information in OMIM
Source: Online Mendelian Inheritance in Man, OMIM®. McKusick-Nathans Institute of Genetic Medicine,
Johns Hopkins University (Baltimore, MD), May, 2012.
World Wide Web URL: http://omim.org/
World Wide Web URL: http://omim.org/
Screening
Validation: In vitro validation
Validation: In vivo validation
Characterization
Functional consequence
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top
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Screening
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| Experimental screening | Non-experimental screening | Reference | ||||||||
| TRP channel construct | Interactor source | |||||||||
| TRP channel | Interactor | Method | Species | Region | Species | Organ/tissue | Sample type | |||
| TRPC5 |
|
Neurabin-1 | Affinity purification-mass spectrometry | Endogenous protein | Rat | Brain | Cerebral cortex lysates | 16025302 | ||
(
:
click the arrow icon to show interactions only between the corresponding TRP channel and the interactor)
:
click the arrow icon to show interactions only between the corresponding TRP channel and the interactor)







Screening