Neurabin-1 / TRP channels
Name: Neurabin-1
(Neurabin-1)
Official Symbol: PPP1R9A
provided by HGNC
Function:
Binds to actin filaments (F-actin) and shows cross-linking activity. Binds along the sides of the F-actin. May be involved in neurite formation. Inhibits protein phosphatase 1-alpha activity (By similarity).
Source: Reorganizing the protein space at the Universal Protein Resource (UniProt)
Nucleic Acids Res. 40: D71-D75 (2012).
Species | External DB | |||||||||
---|---|---|---|---|---|---|---|---|---|---|
Entrez Gene | UniprotKB | DIP | IntAct | MINT | BioGRID | STRING | IUPHAR-DB | KEGG | OMIM | |
Human
|
55607 | Q9ULJ8 | DIP-41131N | Q9ULJ8 | MINT-106754 | 120747 | Q9ULJ8 | hsa:55607 | 602468 | |
Mouse
|
243725 | Q7TN74 | DIP-44293N | MINT-4600266 | 232551 | Q7TN74 | mmu:243725 | |||
Rat
|
84685 | O35867 | DIP-40850N | MINT-107263 | 250039 | O35867 | rno:84685 |
PPI pairs:
Biological Process:
- GO:0030154 : cell differentiation
- GO:0007399 : nervous system development
Source: The Gene Ontology Consortium. Gene ontology: tool for the unification of biology. Nat. Genet.. May 2000;25(1):25-9.
World Wide Web URL: http://www.geneontology.org/
World Wide Web URL: http://www.geneontology.org/
Disease:
No information in OMIM
Source: Online Mendelian Inheritance in Man, OMIM®. McKusick-Nathans Institute of Genetic Medicine,
Johns Hopkins University (Baltimore, MD), May, 2012.
World Wide Web URL: http://omim.org/
World Wide Web URL: http://omim.org/
Screening Validation: In vitro validation Validation: In vivo validation Characterization Functional consequence | top |
Screening | ||||||||||
---|---|---|---|---|---|---|---|---|---|---|
Experimental screening | Non-experimental screening | Reference | ||||||||
TRP channel construct | Interactor source | |||||||||
TRP channel | Interactor | Method | Species | Region | Species | Organ/tissue | Sample type | |||
TRPC5 | Neurabin-1 | Affinity purification-mass spectrometry | Endogenous protein | Rat | Brain | Cerebral cortex lysates | 16025302 |
(:
click the arrow icon to show interactions only between the corresponding TRP channel and the interactor)