Neurofascin / TRP channels
Name: Neurofascin
(Neurofascin)
Official Symbol: NFASC
provided by HGNC
Function:
Cell adhesion, ankyrin-binding protein which may be involved in neurite extension, axonal guidance, synaptogenesis, myelination and neuron-glial cell interactions (By similarity).
Source: Reorganizing the protein space at the Universal Protein Resource (UniProt)
Nucleic Acids Res. 40: D71-D75 (2012).
Species |
External DB
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Entrez Gene | UniprotKB | DIP | IntAct | MINT | BioGRID | STRING | IUPHAR-DB | KEGG | OMIM | |
Human
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23114![]() |
O94856![]() |
O94856![]() |
MINT-2798373![]() |
116737![]() |
O94856![]() |
hsa:23114![]() |
609145![]() |
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Mouse
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269116![]() |
Q810U3![]() |
Q810U3![]() |
234609![]() |
Q810U3![]() |
mmu:269116![]() |
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Rat
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116690![]() |
P97685![]() |
250572![]() |
P97685![]() |
rno:116690![]() |
PPI pairs:
Biological Process:
- GO:0007411
: axon guidance
- GO:0007155
: cell adhesion
- GO:0042552
: myelination
- GO:0030913
: paranodal junction assembly
- GO:0007422
: peripheral nervous system development
- GO:0071205
: protein localization to juxtaparanode region of axon
- GO:0002175
: protein localization to paranode region of axon
- GO:0050808
: synapse organization
Source: The Gene Ontology Consortium. Gene ontology: tool for the unification of biology. Nat. Genet.. May 2000;25(1):25-9.
World Wide Web URL: http://www.geneontology.org/
World Wide Web URL: http://www.geneontology.org/
Disease:
No information in OMIM
Source: Online Mendelian Inheritance in Man, OMIM®. McKusick-Nathans Institute of Genetic Medicine,
Johns Hopkins University (Baltimore, MD), May, 2012.
World Wide Web URL: http://omim.org/
World Wide Web URL: http://omim.org/
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Screening
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Experimental screening | Non-experimental screening | Reference | ||||||||
TRP channel construct | Interactor source | |||||||||
TRP channel | Interactor | Method | Species | Region | Species | Organ/tissue | Sample type | |||
TRPC3 |
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Neurofascin | Affinity purification-mass spectrometry | Not used as a bait | Rat | Brain | Crude membranes | 18205297 |
(
:
click the arrow icon to show interactions only between the corresponding TRP channel and the interactor)
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