Neurofascin / TRP channels
Name: Neurofascin
(Neurofascin)
Official Symbol: NFASC
provided by HGNC
Function:
Cell adhesion, ankyrin-binding protein which may be involved in neurite extension, axonal guidance, synaptogenesis, myelination and neuron-glial cell interactions (By similarity).
Source: Reorganizing the protein space at the Universal Protein Resource (UniProt)
Nucleic Acids Res. 40: D71-D75 (2012).
| Species |
External DB
|
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|---|---|---|---|---|---|---|---|---|---|---|
| Entrez Gene | UniprotKB | DIP | IntAct | MINT | BioGRID | STRING | IUPHAR-DB | KEGG | OMIM | |
Human
|
23114 |
O94856 |
O94856 |
MINT-2798373 |
116737 |
O94856 |
hsa:23114 |
609145 |
||
Mouse
|
269116 |
Q810U3 |
Q810U3 |
234609 |
Q810U3 |
mmu:269116 |
||||
Rat
|
116690 |
P97685 |
250572 |
P97685 |
rno:116690 |
|||||
PPI pairs:
Biological Process:
- GO:0007411
: axon guidance - GO:0007155
: cell adhesion - GO:0042552
: myelination - GO:0030913
: paranodal junction assembly - GO:0007422
: peripheral nervous system development - GO:0071205
: protein localization to juxtaparanode region of axon - GO:0002175
: protein localization to paranode region of axon - GO:0050808
: synapse organization
Source: The Gene Ontology Consortium. Gene ontology: tool for the unification of biology. Nat. Genet.. May 2000;25(1):25-9.
World Wide Web URL: http://www.geneontology.org/
World Wide Web URL: http://www.geneontology.org/
Disease:
No information in OMIM
Source: Online Mendelian Inheritance in Man, OMIM®. McKusick-Nathans Institute of Genetic Medicine,
Johns Hopkins University (Baltimore, MD), May, 2012.
World Wide Web URL: http://omim.org/
World Wide Web URL: http://omim.org/
Screening
Validation: In vitro validation
Validation: In vivo validation
Characterization
Functional consequence
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top
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Screening
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| Experimental screening | Non-experimental screening | Reference | ||||||||
| TRP channel construct | Interactor source | |||||||||
| TRP channel | Interactor | Method | Species | Region | Species | Organ/tissue | Sample type | |||
| TRPC3 |
|
Neurofascin | Affinity purification-mass spectrometry | Not used as a bait | Rat | Brain | Crude membranes | 18205297 | ||
(
:
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:
click the arrow icon to show interactions only between the corresponding TRP channel and the interactor)







Screening