Neuronatin / TRP channels
Name: Neuronatin
(Neuronatin)
Official Symbol: NNAT
provided by HGNC
Function:
May participate in the maintenance of segment identity in the hindbrain and pituitary development, and maturation or maintenance of the overall structure of the nervous system. May function as a regulatory subunit of ion channels.
Source: Reorganizing the protein space at the Universal Protein Resource (UniProt)
Nucleic Acids Res. 40: D71-D75 (2012).
Species | External DB | |||||||||
---|---|---|---|---|---|---|---|---|---|---|
Entrez Gene | UniprotKB | DIP | IntAct | MINT | BioGRID | STRING | IUPHAR-DB | KEGG | OMIM | |
Human
|
4826 | Q16517 | Q16517 | 110890 | Q16517 | hsa:4826 | 603106 | |||
Mouse
|
18111 | Q61979 | 201796 | Q61979 | mmu:18111 | |||||
Rat
|
94270 | Q62649 | 250189 | Q62649 | rno:94270 |
PPI pairs:
Biological Process:
- GO:0007420 : brain development
- GO:0030182 : neuron differentiation
- GO:0032024 : positive regulation of insulin secretion
- GO:0009249 : protein lipoylation
- GO:0032880 : regulation of protein localization
- GO:0009749 : response to glucose stimulus
- GO:0006810 : transport
Source: The Gene Ontology Consortium. Gene ontology: tool for the unification of biology. Nat. Genet.. May 2000;25(1):25-9.
World Wide Web URL: http://www.geneontology.org/
World Wide Web URL: http://www.geneontology.org/
Disease:
No information in OMIM
Source: Online Mendelian Inheritance in Man, OMIM®. McKusick-Nathans Institute of Genetic Medicine,
Johns Hopkins University (Baltimore, MD), May, 2012.
World Wide Web URL: http://omim.org/
World Wide Web URL: http://omim.org/
Screening Validation: In vitro validation Validation: In vivo validation Characterization Functional consequence | top |
Screening | ||||||||||
---|---|---|---|---|---|---|---|---|---|---|
Experimental screening | Non-experimental screening | Reference | ||||||||
TRP channel construct | Interactor source | |||||||||
TRP channel | Interactor | Method | Species | Region | Species | Organ/tissue | Sample type | |||
TRPV1 | Neuronatin | Yeast two-hybrid | Rat | 1-432 | Human | Fetal brain | cDNA library | 17074976 |
(:
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