PGK1 / TRP channels
Name: Phosphoglycerate kinase 1
(PGK1)
Official Symbol: PGK1
provided by HGNC
Function:
In addition to its role as a glycolytic enzyme, it seems that PGK-1 acts as a polymerase alpha cofactor protein (primer recognition protein).
Source: Reorganizing the protein space at the Universal Protein Resource (UniProt)
Nucleic Acids Res. 40: D71-D75 (2012).
Species |
External DB
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Entrez Gene | UniprotKB | DIP | IntAct | MINT | BioGRID | STRING | IUPHAR-DB | KEGG | OMIM | |
Human
![]() |
5230![]() |
P00558![]() |
P00558![]() |
MINT-1131047![]() |
111251![]() |
P00558![]() |
hsa:5230![]() |
311800![]() |
||
Mouse
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18655![]() |
P09411![]() |
P09411![]() |
202133![]() |
P09411![]() |
mmu:18655![]() |
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Rat
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24644![]() |
P16617![]() |
MINT-4577521![]() |
246779![]() |
P16617![]() |
rno:24644![]() |
PPI pairs:
Biological Process:
- GO:0006094
: gluconeogenesis
- GO:0006096
: glycolysis
- GO:0044281
: small molecule metabolic process
Source: The Gene Ontology Consortium. Gene ontology: tool for the unification of biology. Nat. Genet.. May 2000;25(1):25-9.
World Wide Web URL: http://www.geneontology.org/
World Wide Web URL: http://www.geneontology.org/
Disease:
- OMIM:311800
: Phosphoglycerate kinase 1 deficiency (OMIM:300653
)
Source: Online Mendelian Inheritance in Man, OMIM®. McKusick-Nathans Institute of Genetic Medicine,
Johns Hopkins University (Baltimore, MD), May, 2012.
World Wide Web URL: http://omim.org/
World Wide Web URL: http://omim.org/
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Screening
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Experimental screening | Non-experimental screening | Reference | ||||||||
TRP channel construct | Interactor source | |||||||||
TRP channel | Interactor | Method | Species | Region | Species | Organ/tissue | Sample type | |||
TRPC3 |
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PGK1 | Affinity purification-mass spectrometry | Not used as a bait | Rat | Brain | Crude membranes | 18205297 |
(
:
click the arrow icon to show interactions only between the corresponding TRP channel and the interactor)
