PLAGL1 / TRP channels
Name: Zinc finger protein PLAGL1
(PLAGL1)
Official Symbol: PLAGL1
provided by HGNC
Function:
Shows weak transcriptional activatory activity. Transcriptional regulator of the type 1 receptor for pituitary adenylate cyclase-activating polypeptide.
Source: Reorganizing the protein space at the Universal Protein Resource (UniProt)
Nucleic Acids Res. 40: D71-D75 (2012).
Species | External DB | |||||||||
---|---|---|---|---|---|---|---|---|---|---|
Entrez Gene | UniprotKB | DIP | IntAct | MINT | BioGRID | STRING | IUPHAR-DB | KEGG | OMIM | |
Human
|
5325 | Q9UM63 | DIP-57558N | MINT-1188459 | 111341 | Q9UM63 | hsa:5325 | 603044 | ||
Mouse
|
22634 | Q9JLQ4 | DIP-40450N | Q9JLQ4 | 204626 | Q9JLQ4 | mmu:22634 | |||
Rat
|
25157 | P70616 | 247222 | P70616 | rno:25157 |
PPI pairs:
Biological Process:
- GO:0007050 : cell cycle arrest
- GO:0006917 : induction of apoptosis
- GO:0045944 : positive regulation of transcription from RNA polymerase II promoter
- GO:0006351 : transcription, DNA-dependent
Source: The Gene Ontology Consortium. Gene ontology: tool for the unification of biology. Nat. Genet.. May 2000;25(1):25-9.
World Wide Web URL: http://www.geneontology.org/
World Wide Web URL: http://www.geneontology.org/
Disease:
No information in OMIM
Source: Online Mendelian Inheritance in Man, OMIM®. McKusick-Nathans Institute of Genetic Medicine,
Johns Hopkins University (Baltimore, MD), May, 2012.
World Wide Web URL: http://omim.org/
World Wide Web URL: http://omim.org/
Screening Validation: In vitro validation Validation: In vivo validation Characterization Functional consequence | top |
Screening | ||||||||||
---|---|---|---|---|---|---|---|---|---|---|
Experimental screening | Non-experimental screening | Reference | ||||||||
TRP channel construct | Interactor source | |||||||||
TRP channel | Interactor | Method | Species | Region | Species | Organ/tissue | Sample type | |||
TRPV1 | PLAGL1 | Yeast two-hybrid | Rat | 1-432 | Human | Fetal brain | cDNA library | 17074976 |
(:
click the arrow icon to show interactions only between the corresponding TRP channel and the interactor)