RPL12 / TRP channels
Name: 60S ribosomal protein L12
(RPL12)
Official Symbol: RPL12
provided by HGNC
Function:
Binds directly to 26S ribosomal RNA (By similarity).
Source: Reorganizing the protein space at the Universal Protein Resource (UniProt)
Nucleic Acids Res. 40: D71-D75 (2012).
Species | External DB | |||||||||
---|---|---|---|---|---|---|---|---|---|---|
Entrez Gene | UniprotKB | DIP | IntAct | MINT | BioGRID | STRING | IUPHAR-DB | KEGG | OMIM | |
Human
|
6136 | P30050 | DIP-33208N | P30050 | MINT-2802291 | 112056 | P30050 | hsa:6136 | 180475 | |
Mouse
|
269261 | P35979 | DIP-51690N | P35979 | MINT-1870314 | 234630 | P35979 | mmu:269261 | ||
Rat
|
296644 | D3ZJE2 | 255434 | rno:296644 |
PPI pairs:
Biological Process:
- GO:0000184 : nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
- GO:0006614 : SRP-dependent cotranslational protein targeting to membrane
- GO:0006414 : translational elongation
- GO:0006413 : translational initiation
- GO:0006415 : translational termination
- GO:0019083 : viral transcription
Source: The Gene Ontology Consortium. Gene ontology: tool for the unification of biology. Nat. Genet.. May 2000;25(1):25-9.
World Wide Web URL: http://www.geneontology.org/
World Wide Web URL: http://www.geneontology.org/
Disease:
No information in OMIM
Source: Online Mendelian Inheritance in Man, OMIM®. McKusick-Nathans Institute of Genetic Medicine,
Johns Hopkins University (Baltimore, MD), May, 2012.
World Wide Web URL: http://omim.org/
World Wide Web URL: http://omim.org/
Screening Validation: In vitro validation Validation: In vivo validation Characterization Functional consequence | top |
Screening | ||||||||||
---|---|---|---|---|---|---|---|---|---|---|
Experimental screening | Non-experimental screening | Reference | ||||||||
TRP channel construct | Interactor source | |||||||||
TRP channel | Interactor | Method | Species | Region | Species | Organ/tissue | Sample type | |||
TRPV1 | RPL12 | Yeast two-hybrid | Rat | 1-432 | Human | Fetal brain | cDNA library | 17074976 |
(:
click the arrow icon to show interactions only between the corresponding TRP channel and the interactor)