SEC13 / TRP channels
Name: Protein SEC13 homolog
(SEC13)
Official Symbol: SEC13
provided by HGNC
Function:
Functions as a component of the nuclear pore complex (NPC) and the COPII coat. At the endoplasmic reticulum, SEC13 is involved in the biogenesis of COPII-coated vesicles.
Source: Reorganizing the protein space at the Universal Protein Resource (UniProt)
Nucleic Acids Res. 40: D71-D75 (2012).
| Species |
External DB
|
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|---|---|---|---|---|---|---|---|---|---|---|
| Entrez Gene | UniprotKB | DIP | IntAct | MINT | BioGRID | STRING | IUPHAR-DB | KEGG | OMIM | |
Human
|
6396 |
P55735 |
DIP-39091N |
P55735 |
MINT-1154053 |
112296 |
P55735 |
hsa:6396 |
600152 |
|
Mouse
|
110379 |
Q9D1M0 |
Q9D1M0 |
MINT-1865076 |
225548 |
Q9D1M0 |
mmu:110379 |
|||
Rat
|
297522 |
Q5XFW8 |
MINT-4577232 |
255603 |
Q5XFW8 |
rno:297522 |
||||
PPI pairs:
Biological Process:
- GO:0019886
: antigen processing and presentation of exogenous peptide antigen via MHC class II - GO:0002474
: antigen processing and presentation of peptide antigen via MHC class I - GO:0048208
: COPII vesicle coating - GO:0006886
: intracellular protein transport - GO:0000236
: mitotic prometaphase - GO:0051028
: mRNA transport - GO:0043687
: post-translational protein modification - GO:0018279
: protein N-linked glycosylation via asparagine
Source: The Gene Ontology Consortium. Gene ontology: tool for the unification of biology. Nat. Genet.. May 2000;25(1):25-9.
World Wide Web URL: http://www.geneontology.org/
World Wide Web URL: http://www.geneontology.org/
Disease:
No information in OMIM
Source: Online Mendelian Inheritance in Man, OMIM®. McKusick-Nathans Institute of Genetic Medicine,
Johns Hopkins University (Baltimore, MD), May, 2012.
World Wide Web URL: http://omim.org/
World Wide Web URL: http://omim.org/
Screening
Validation: In vitro validation
Validation: In vivo validation
Characterization
Functional consequence
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top
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Screening
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| Experimental screening | Non-experimental screening | Reference | ||||||||
| TRP channel construct | Interactor source | |||||||||
| TRP channel | Interactor | Method | Species | Region | Species | Organ/tissue | Sample type | |||
| TRPML1 |
|
SEC13 | Affinity purification-mass spectrometry | Human | 1-66 | HeLa lysates | 19864416 | |||
(
:
click the arrow icon to show interactions only between the corresponding TRP channel and the interactor)
:
click the arrow icon to show interactions only between the corresponding TRP channel and the interactor)







Screening