SEC13 / TRP channels
Name: Protein SEC13 homolog
(SEC13)
Official Symbol: SEC13
provided by HGNC
Function:
Functions as a component of the nuclear pore complex (NPC) and the COPII coat. At the endoplasmic reticulum, SEC13 is involved in the biogenesis of COPII-coated vesicles.
Source: Reorganizing the protein space at the Universal Protein Resource (UniProt)
Nucleic Acids Res. 40: D71-D75 (2012).
Species | External DB | |||||||||
---|---|---|---|---|---|---|---|---|---|---|
Entrez Gene | UniprotKB | DIP | IntAct | MINT | BioGRID | STRING | IUPHAR-DB | KEGG | OMIM | |
Human
|
6396 | P55735 | DIP-39091N | P55735 | MINT-1154053 | 112296 | P55735 | hsa:6396 | 600152 | |
Mouse
|
110379 | Q9D1M0 | Q9D1M0 | MINT-1865076 | 225548 | Q9D1M0 | mmu:110379 | |||
Rat
|
297522 | Q5XFW8 | MINT-4577232 | 255603 | Q5XFW8 | rno:297522 |
PPI pairs:
Biological Process:
- GO:0019886 : antigen processing and presentation of exogenous peptide antigen via MHC class II
- GO:0002474 : antigen processing and presentation of peptide antigen via MHC class I
- GO:0048208 : COPII vesicle coating
- GO:0006886 : intracellular protein transport
- GO:0000236 : mitotic prometaphase
- GO:0051028 : mRNA transport
- GO:0043687 : post-translational protein modification
- GO:0018279 : protein N-linked glycosylation via asparagine
Source: The Gene Ontology Consortium. Gene ontology: tool for the unification of biology. Nat. Genet.. May 2000;25(1):25-9.
World Wide Web URL: http://www.geneontology.org/
World Wide Web URL: http://www.geneontology.org/
Disease:
No information in OMIM
Source: Online Mendelian Inheritance in Man, OMIM®. McKusick-Nathans Institute of Genetic Medicine,
Johns Hopkins University (Baltimore, MD), May, 2012.
World Wide Web URL: http://omim.org/
World Wide Web URL: http://omim.org/
Screening Validation: In vitro validation Validation: In vivo validation Characterization Functional consequence | top |
Screening | ||||||||||
---|---|---|---|---|---|---|---|---|---|---|
Experimental screening | Non-experimental screening | Reference | ||||||||
TRP channel construct | Interactor source | |||||||||
TRP channel | Interactor | Method | Species | Region | Species | Organ/tissue | Sample type | |||
TRPML1 | SEC13 | Affinity purification-mass spectrometry | Human | 1-66 | HeLa lysates | 19864416 |
(:
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