SEC13 / TRP channels
Name: Protein SEC13 homolog
(SEC13)
Official Symbol: SEC13
provided by HGNC
Function:
Functions as a component of the nuclear pore complex (NPC) and the COPII coat. At the endoplasmic reticulum, SEC13 is involved in the biogenesis of COPII-coated vesicles.
Source: Reorganizing the protein space at the Universal Protein Resource (UniProt)
Nucleic Acids Res. 40: D71-D75 (2012).
Species |
External DB
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Entrez Gene | UniprotKB | DIP | IntAct | MINT | BioGRID | STRING | IUPHAR-DB | KEGG | OMIM | |
Human
![]() |
6396![]() |
P55735![]() |
DIP-39091N![]() |
P55735![]() |
MINT-1154053![]() |
112296![]() |
P55735![]() |
hsa:6396![]() |
600152![]() |
|
Mouse
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110379![]() |
Q9D1M0![]() |
Q9D1M0![]() |
MINT-1865076![]() |
225548![]() |
Q9D1M0![]() |
mmu:110379![]() |
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Rat
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297522![]() |
Q5XFW8![]() |
MINT-4577232![]() |
255603![]() |
Q5XFW8![]() |
rno:297522![]() |
PPI pairs:
Biological Process:
- GO:0019886
: antigen processing and presentation of exogenous peptide antigen via MHC class II
- GO:0002474
: antigen processing and presentation of peptide antigen via MHC class I
- GO:0048208
: COPII vesicle coating
- GO:0006886
: intracellular protein transport
- GO:0000236
: mitotic prometaphase
- GO:0051028
: mRNA transport
- GO:0043687
: post-translational protein modification
- GO:0018279
: protein N-linked glycosylation via asparagine
Source: The Gene Ontology Consortium. Gene ontology: tool for the unification of biology. Nat. Genet.. May 2000;25(1):25-9.
World Wide Web URL: http://www.geneontology.org/
World Wide Web URL: http://www.geneontology.org/
Disease:
No information in OMIM
Source: Online Mendelian Inheritance in Man, OMIM®. McKusick-Nathans Institute of Genetic Medicine,
Johns Hopkins University (Baltimore, MD), May, 2012.
World Wide Web URL: http://omim.org/
World Wide Web URL: http://omim.org/
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Screening
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Experimental screening | Non-experimental screening | Reference | ||||||||
TRP channel construct | Interactor source | |||||||||
TRP channel | Interactor | Method | Species | Region | Species | Organ/tissue | Sample type | |||
TRPML1 |
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SEC13 | Affinity purification-mass spectrometry | Human | 1-66 | HeLa lysates | 19864416 |
(
:
click the arrow icon to show interactions only between the corresponding TRP channel and the interactor)
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