STOML1 / TRP channels
Name: Stomatin-like protein 1
(STOML1)
Official Symbol: STOML1
provided by HGNC
Function:
Source: Reorganizing the protein space at the Universal Protein Resource (UniProt)
Nucleic Acids Res. 40: D71-D75 (2012).
Species | External DB | |||||||||
---|---|---|---|---|---|---|---|---|---|---|
Entrez Gene | UniprotKB | DIP | IntAct | MINT | BioGRID | STRING | IUPHAR-DB | KEGG | OMIM | |
Human
|
9399 | Q9UBI4 | DIP-56169N | Q9UBI4 | 114796 | Q9UBI4 | hsa:9399 | 608326 | ||
Mouse
|
69106 | Q8CI66 | 213233 | Q8CI66 | mmu:69106 | |||||
Rat
|
300748 | D4A7E9 | 256696 | rno:300748 |
PPI pairs:
Biological Process:
No information in Gene Ontology
Source: The Gene Ontology Consortium. Gene ontology: tool for the unification of biology. Nat. Genet.. May 2000;25(1):25-9.
World Wide Web URL: http://www.geneontology.org/
World Wide Web URL: http://www.geneontology.org/
Disease:
No information in OMIM
Source: Online Mendelian Inheritance in Man, OMIM®. McKusick-Nathans Institute of Genetic Medicine,
Johns Hopkins University (Baltimore, MD), May, 2012.
World Wide Web URL: http://omim.org/
World Wide Web URL: http://omim.org/
Screening Validation: In vitro validation Validation: In vivo validation Characterization Functional consequence | top |
Screening | ||||||||||
---|---|---|---|---|---|---|---|---|---|---|
Experimental screening | Non-experimental screening | Reference | ||||||||
TRP channel construct | Interactor source | |||||||||
TRP channel | Interactor | Method | Species | Region | Species | Organ/tissue | Sample type | |||
TRPML1 | STOML1 | Affinity purification-mass spectrometry | Mouse | Full-length | Mouse | RAW264.7 macrophages | Lysates | 23418601 |
(:
click the arrow icon to show interactions only between the corresponding TRP channel and the interactor)
Screening Validation: In vitro validation Validation: In vivo validation Characterization Functional consequence | top |
Validation: In vivo validation | ||||||||||
---|---|---|---|---|---|---|---|---|---|---|
Assay with endogenous proteins | Assay with overexpressed proteins | Reference | ||||||||
Cell or tissue | Cell or tissue | TRP channel construct | Interactor construct | |||||||
TRP channel | Interactor | Method | Species | Region | Species | Region | ||||
TRPML1 | STOML1 | Co-immunofluorescence staining | RAW264.7 macrophage | Mouse | Full-length | Mouse | Full-length | 23418601 | ||
TRPML1 | STOML1 | Co-immunoprecipitation | HeLa | Mouse | Full-length | Mouse | Full-length | 23418601 | ||
TRPML1 | STOML1 | Co-immunoprecipitation | RAW264.7 macrophage | Mouse | Full-length | Not used | 23418601 |
(:
click the arrow icon to show interactions only between the corresponding TRP channel and the interactor)