TMEM115 / TRP channels
  Name: Transmembrane protein 115  
  (TMEM115)
  Official Symbol: TMEM115
  
    provided by HGNC
  
  Function:
  
Source: Reorganizing the protein space at the Universal Protein Resource (UniProt)
Nucleic Acids Res. 40: D71-D75 (2012).
    | Species | External DB   | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Entrez Gene | UniprotKB | DIP | IntAct | MINT | BioGRID | STRING | IUPHAR-DB | KEGG | OMIM | |
| Human   | 11070  | Q12893  | 116254  | Q12893  | hsa:11070  | 607069  | ||||
| Mouse   | 56395  | Q9WUH1  | 207950  | Q9WUH1  | mmu:56395  | |||||
| Rat   | 363136  | D3ZE59  | 263987  | rno:363136  | ||||||
      PPI pairs:
    
    
    Biological Process:
    
      
    - GO:0008285  : negative regulation of cell proliferation : negative regulation of cell proliferation
- GO:0001302  : replicative cell aging : replicative cell aging
Source: The Gene Ontology Consortium. Gene ontology: tool for the unification of biology. Nat. Genet.. May 2000;25(1):25-9.
World Wide Web URL: http://www.geneontology.org/
World Wide Web URL: http://www.geneontology.org/
    Disease:
  No information in OMIM 
    
Source: Online Mendelian Inheritance in Man, OMIM®. McKusick-Nathans Institute of Genetic Medicine, 
Johns Hopkins University (Baltimore, MD), May, 2012. 
World Wide Web URL: http://omim.org/
World Wide Web URL: http://omim.org/
|  Screening  Validation: In vitro validation  Validation: In vivo validation  Characterization  Functional consequence |  top | 
| Screening   | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Experimental screening | Non-experimental screening | Reference | ||||||||
| TRP channel construct | Interactor source | |||||||||
| TRP channel | Interactor | Method | Species | Region | Species | Organ/tissue | Sample type | |||
| TRPV1 |   | TMEM115 | Yeast two-hybrid | Rat | 1-432 | Human | Fetal brain | cDNA library | 17074976 | |
  ( : 
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: 
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   : 
  click the arrow icon to show interactions only between the corresponding TRP channel and the interactor)
: 
  click the arrow icon to show interactions only between the corresponding TRP channel and the interactor)




