TUBGCP2 / TRP channels
Name: Gamma-tubulin complex component 2
(TUBGCP2)
Official Symbol: TUBGCP2
provided by HGNC
Function:
Gamma-tubulin complex is necessary for microtubule nucleation at the centrosome.
Source: Reorganizing the protein space at the Universal Protein Resource (UniProt)
Nucleic Acids Res. 40: D71-D75 (2012).
| Species |
External DB
|
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Entrez Gene | UniprotKB | DIP | IntAct | MINT | BioGRID | STRING | IUPHAR-DB | KEGG | OMIM | |
Human
|
10844 |
Q9BSJ2 |
DIP-38141N |
Q9BSJ2 |
MINT-1152554 |
116055 |
Q9BSJ2 |
hsa:10844 |
||
Mouse
|
74237 |
Q921G8 |
DIP-56688N |
Q921G8 |
MINT-4611145 |
216597 |
Q921G8 |
mmu:74237 |
||
Rat
|
309098 |
B2RYP8 |
DIP-57243N |
MINT-7138097 |
259257 |
B2RYP8 |
rno:309098 |
|||
PPI pairs:
Biological Process:
- GO:0000086
: G2/M transition of mitotic cell cycle - GO:0007020
: microtubule nucleation - GO:0006461
: protein complex assembly
Source: The Gene Ontology Consortium. Gene ontology: tool for the unification of biology. Nat. Genet.. May 2000;25(1):25-9.
World Wide Web URL: http://www.geneontology.org/
World Wide Web URL: http://www.geneontology.org/
Disease:
No information in OMIM
Source: Online Mendelian Inheritance in Man, OMIM®. McKusick-Nathans Institute of Genetic Medicine,
Johns Hopkins University (Baltimore, MD), May, 2012.
World Wide Web URL: http://omim.org/
World Wide Web URL: http://omim.org/
Screening
Validation: In vitro validation
Validation: In vivo validation
Characterization
Functional consequence
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top
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Screening
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| Experimental screening | Non-experimental screening | Reference | ||||||||
| TRP channel construct | Interactor source | |||||||||
| TRP channel | Interactor | Method | Species | Region | Species | Organ/tissue | Sample type | |||
| TRPC5 |
|
TUBGCP2 | Affinity purification-mass spectrometry | Endogenous protein | Rat | Brain | Cerebral cortex lysates | 16025302 | ||
(
:
click the arrow icon to show interactions only between the corresponding TRP channel and the interactor)
:
click the arrow icon to show interactions only between the corresponding TRP channel and the interactor)







Screening