TUBGCP3 / TRP channels
Name: Gamma-tubulin complex component 3
(TUBGCP3)
Official Symbol: TUBGCP3
provided by HGNC
Function:
Gamma-tubulin complex is necessary for microtubule nucleation at the centrosome.
Source: Reorganizing the protein space at the Universal Protein Resource (UniProt)
Nucleic Acids Res. 40: D71-D75 (2012).
| Species |
External DB
|
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Entrez Gene | UniprotKB | DIP | IntAct | MINT | BioGRID | STRING | IUPHAR-DB | KEGG | OMIM | |
Human
|
10426 |
Q96CW5 |
DIP-50822N |
Q96CW5 |
MINT-3051799 |
115695 |
Q96CW5 |
hsa:10426 |
||
Mouse
|
259279 |
P58854 |
DIP-56464N |
P58854 |
UNK-5381110 |
234417 |
P58854 |
mmu:259279 |
||
Rat
|
306599 |
D3ZMR7 |
258501 |
rno:306599 |
||||||
PPI pairs:
Biological Process:
- GO:0000086
: G2/M transition of mitotic cell cycle - GO:0007020
: microtubule nucleation - GO:0007338
: single fertilization
Source: The Gene Ontology Consortium. Gene ontology: tool for the unification of biology. Nat. Genet.. May 2000;25(1):25-9.
World Wide Web URL: http://www.geneontology.org/
World Wide Web URL: http://www.geneontology.org/
Disease:
No information in OMIM
Source: Online Mendelian Inheritance in Man, OMIM®. McKusick-Nathans Institute of Genetic Medicine,
Johns Hopkins University (Baltimore, MD), May, 2012.
World Wide Web URL: http://omim.org/
World Wide Web URL: http://omim.org/
Screening
Validation: In vitro validation
Validation: In vivo validation
Characterization
Functional consequence
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top
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Screening
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|---|---|---|---|---|---|---|---|---|---|---|
| Experimental screening | Non-experimental screening | Reference | ||||||||
| TRP channel construct | Interactor source | |||||||||
| TRP channel | Interactor | Method | Species | Region | Species | Organ/tissue | Sample type | |||
| TRPC5 |
|
TUBGCP3 | Affinity purification-mass spectrometry | Endogenous protein | Rat | Brain | Cerebral cortex lysates | 16025302 | ||
(
:
click the arrow icon to show interactions only between the corresponding TRP channel and the interactor)
:
click the arrow icon to show interactions only between the corresponding TRP channel and the interactor)







Screening