VDAC3 / TRP channels
Name: Voltage-dependent anion-selective channel protein 3
(VDAC3)
Official Symbol: VDAC3
provided by HGNC
Function:
Forms a channel through the mitochondrial outer membrane that allows diffusion of small hydrophilic molecules (By similarity).
Source: Reorganizing the protein space at the Universal Protein Resource (UniProt)
Nucleic Acids Res. 40: D71-D75 (2012).
| Species |
External DB
|
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Entrez Gene | UniprotKB | DIP | IntAct | MINT | BioGRID | STRING | IUPHAR-DB | KEGG | OMIM | |
Human
|
7419 |
Q9Y277 |
DIP-32861N |
Q9Y277 |
MINT-1395020 |
113262 |
Q9Y277 |
hsa:7419 |
610029 |
|
Mouse
|
22335 |
Q60931 |
DIP-32241N |
Q60931 |
MINT-1858022 |
204509 |
Q60931 |
mmu:22335 |
||
Rat
|
83532 |
Q9R1Z0 |
DIP-53061N |
Q9R1Z0 |
MINT-4620461 |
249748 |
Q9R1Z0 |
rno:83532 |
||
Biological Process:
- GO:0015853
: adenine transport
Source: The Gene Ontology Consortium. Gene ontology: tool for the unification of biology. Nat. Genet.. May 2000;25(1):25-9.
World Wide Web URL: http://www.geneontology.org/
World Wide Web URL: http://www.geneontology.org/
Disease:
No information in OMIM
Source: Online Mendelian Inheritance in Man, OMIM®. McKusick-Nathans Institute of Genetic Medicine,
Johns Hopkins University (Baltimore, MD), May, 2012.
World Wide Web URL: http://omim.org/
World Wide Web URL: http://omim.org/
Screening
Validation: In vitro validation
Validation: In vivo validation
Characterization
Functional consequence
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top
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Screening
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|---|---|---|---|---|---|---|---|---|---|---|
| Experimental screening | Non-experimental screening | Reference | ||||||||
| TRP channel construct | Interactor source | |||||||||
| TRP channel | Interactor | Method | Species | Region | Species | Organ/tissue | Sample type | |||
| TRPC3 |
|
VDAC3 | Affinity purification-mass spectrometry | Not used as a bait | Rat | Brain | Crude membranes | 18205297 | ||
| TRPP1 |
|
VDAC3 | Affinity purification-mass spectrometry | Mouse | Not specified | Mouse | Vascular smooth muscle | MOVAS lysates | 19879844 | |
(
:
click the arrow icon to show interactions only between the corresponding TRP channel and the interactor)
:
click the arrow icon to show interactions only between the corresponding TRP channel and the interactor)







Screening