VDAC3 / TRP channels
Name: Voltage-dependent anion-selective channel protein 3
(VDAC3)
Official Symbol: VDAC3
provided by HGNC
Function:
Forms a channel through the mitochondrial outer membrane that allows diffusion of small hydrophilic molecules (By similarity).
Source: Reorganizing the protein space at the Universal Protein Resource (UniProt)
Nucleic Acids Res. 40: D71-D75 (2012).
Species | External DB | |||||||||
---|---|---|---|---|---|---|---|---|---|---|
Entrez Gene | UniprotKB | DIP | IntAct | MINT | BioGRID | STRING | IUPHAR-DB | KEGG | OMIM | |
Human
|
7419 | Q9Y277 | DIP-32861N | Q9Y277 | MINT-1395020 | 113262 | Q9Y277 | hsa:7419 | 610029 | |
Mouse
|
22335 | Q60931 | DIP-32241N | Q60931 | MINT-1858022 | 204509 | Q60931 | mmu:22335 | ||
Rat
|
83532 | Q9R1Z0 | DIP-53061N | Q9R1Z0 | MINT-4620461 | 249748 | Q9R1Z0 | rno:83532 |
Biological Process:
- GO:0015853 : adenine transport
Source: The Gene Ontology Consortium. Gene ontology: tool for the unification of biology. Nat. Genet.. May 2000;25(1):25-9.
World Wide Web URL: http://www.geneontology.org/
World Wide Web URL: http://www.geneontology.org/
Disease:
No information in OMIM
Source: Online Mendelian Inheritance in Man, OMIM®. McKusick-Nathans Institute of Genetic Medicine,
Johns Hopkins University (Baltimore, MD), May, 2012.
World Wide Web URL: http://omim.org/
World Wide Web URL: http://omim.org/
Screening Validation: In vitro validation Validation: In vivo validation Characterization Functional consequence | top |
Screening | ||||||||||
---|---|---|---|---|---|---|---|---|---|---|
Experimental screening | Non-experimental screening | Reference | ||||||||
TRP channel construct | Interactor source | |||||||||
TRP channel | Interactor | Method | Species | Region | Species | Organ/tissue | Sample type | |||
TRPC3 | VDAC3 | Affinity purification-mass spectrometry | Not used as a bait | Rat | Brain | Crude membranes | 18205297 | |||
TRPP1 | VDAC3 | Affinity purification-mass spectrometry | Mouse | Not specified | Mouse | Vascular smooth muscle | MOVAS lysates | 19879844 |
(:
click the arrow icon to show interactions only between the corresponding TRP channel and the interactor)